Host-microbiome interactions: the aryl hydrocarbon receptor as a critical node in tryptophan metabolites to brain signaling.

Tryptophan (Trp) is not only a nutrient enhancer but also has systemic effects. Trp metabolites signaling through the well-known aryl hydrocarbon receptor (AhR) constitute the interface of microbiome-gut-brain axis.

However, the pathway through which Trp metabolites affect central nervous system (CNS) function have not been fully elucidated. AhR participates in a broad variety of physiological and pathological processes that also highly relevant to intestinal homeostasis and CNS diseases.

8-Arm PEG-GA

abx085109-10kDa1g 10 kDa; 1 g
EUR 393.6

8-Arm PEG-GA

abx085109-10kDa5g 10 kDa; 5 g
EUR 744

8-Arm PEG-GA

abx085109-20kDa5g 20 kDa; 5 g
EUR 744

8-Arm PEG-GA

abx085109-40kDa1g 40 kDa; 1 g
EUR 427.2

4-Arm PEG-GA

abx085098-100l 100 µl
EUR 250

4-Arm PEG-GA

abx085098-1ml 1 ml Ask for price

4-Arm PEG-GA

abx085098-200l 200 µl
EUR 712.5

8-Arm PEG-GA

abx085109-100l 100 µl
EUR 250

8-Arm PEG-GA

abx085109-1ml 1 ml
EUR 275

8-Arm PEG-GA

abx085109-200l 200 µl
EUR 250

4-Arm PEG-GAS

abx085093-10kDa1g 10 kDa; 1 g
EUR 526.8

4-Arm PEG-GAS

abx085093-10kDa5g 10 kDa; 5 g
EUR 878.4

4-Arm PEG-GAS

abx085093-20kDa5g 20 kDa; 5 g
EUR 878.4

4-Arm PEG-GAS

abx085093-2kDa1g 2 kDa; 1 g
EUR 477.6

4-Arm PEG-GAA

abx085100-10kDa1g 10 kDa; 1 g
EUR 460.8

4-Arm PEG-GAA

abx085100-10kDa5g 10 kDa; 5 g
EUR 760.8

4-Arm PEG-GAA

abx085100-20kDa5g 20 kDa; 5 g
EUR 760.8

4-Arm PEG-GAA

abx085100-2kDa1g 2 kDa; 1 g
EUR 427.2

8-Arm PEG-GAA

abx085111-10kDa1g 10 kDa; 1 g
EUR 393.6

8-Arm PEG-GAA

abx085111-10kDa5g 10 kDa; 5 g
EUR 744

8-Arm PEG-GAA

abx085111-20kDa5g 20 kDa; 5 g
EUR 744

8-Arm PEG-GAA

abx085111-40kDa1g 40 kDa; 1 g
EUR 427.2

8-Arm PEG-GAS

abx085116-10kDa1g 10 kDa; 1 g
EUR 393.6

8-Arm PEG-GAS

abx085116-10kDa5g 10 kDa; 5 g
EUR 744

8-Arm PEG-GAS

abx085116-20kDa5g 20 kDa; 5 g
EUR 744

8-Arm PEG-GAS

abx085116-40kDa1g 40 kDa; 1 g
EUR 427.2

4-Arm PEG-GAS

abx085093-100l 100 µl
EUR 312.5

4-Arm PEG-GAS

abx085093-1ml 1 ml
EUR 350

4-Arm PEG-GAS

abx085093-200l 200 µl
EUR 312.5

4-Arm PEG-GAA

abx085100-100l 100 µl
EUR 275

4-Arm PEG-GAA

abx085100-1ml 1 ml
EUR 300

4-Arm PEG-GAA

abx085100-200l 200 µl
EUR 275

8-Arm PEG-GAA

abx085111-100l 100 µl
EUR 250

8-Arm PEG-GAA

abx085111-1ml 1 ml
EUR 275

8-Arm PEG-GAA

abx085111-200l 200 µl
EUR 250

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abx085116-100l 100 µl
EUR 275

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abx085116-200l 200 µl
EUR 837.5

rHu PEG-GCSF (cGMP)

AK9032-0000 1mg Ask for price

PCL(5K)-PEG-Galactose

abx085406-2kDa1g 2 kDa; 1 g
EUR 684

PCL(5K)-PEG-Galactose, 2K

HE116072-2K-G G
EUR 430.8
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

PCL(5K)-PEG-Galactose

abx085406-100l 100 µl
EUR 762.5

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abx085406-200l 200 µl Ask for price

KRIBIOLISA PEG-GCSF (Pegylated Filgrastim) ELISA

KBBA10 1 x 96 wells
EUR 676.5

AzoDye-1 PEG10 Alkyne

2415-1mg 1 mg
EUR 151
Description: AzoDye-1 PEG10 alkyne is an excellent building block for labeling azide-containing molecules.

PEG3-tetrazine, 1 g

1978-1g 1 g
EUR 793.2

AzoDye-1 PEG10 Succinimidyl Ester

2403-5mg 5 mg
EUR 97
Description: AzoDye-1 PEG10 Succinimidyl Ester is an excellent building block for labeling amino-containing molecules.

JBScreen Membrane 1 (PEG 400 to PEG 2000 MME based)

M-CS-301L 24 solutions
EUR 414
Description: JBScreen Membrane 1 (PEG 400 to PEG 2000 MME based)

PEG3 dicarboxylic acid, 1 g

1715-1g 1 g
EUR 423.6

pEGFP- MD2- 1

PVT10180 2 ug
EUR 361.2

JBScreen Classic 1 (PEG 400 to 3000 based)

M-CS-101L 24 solutions
EUR 249
Description: JBScreen Classic 1 (PEG 400 to 3000 based)

Lenti ORF clone of Peg10 (mGFP-tagged) - Mouse paternally expressed 10 (Peg10), transcript variant 1, encoding isoform 1

MR224445L4 10 µg Ask for price

Peg12 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6370802 1.0 ug DNA
EUR 184.8

pEGFP- 1 Plasmid

PVT1201 2 ug
EUR 319.2

PEG30K-Cys-AEEAc-Fibrinopeptide A (1-15)

4066201.05 0.5 mg
EUR 240.45

PEG30K-Cys-AEEAc-Fibrinopeptide A (1-15)

4066201.1 1 mg
EUR 422.42

PEG30K-Cys-AEEAc-Fibrinopeptide A (1-15)

H-8348.0500 0.5mg
EUR 410.4
Description: Sum Formula: C66H101N17O29S+PEG30K

PEG30K-Cys-AEEAc-Fibrinopeptide A (1-15)

H-8348.1000 1.0mg
EUR 691.2
Description: Sum Formula: C66H101N17O29S+PEG30K

PEG10 sgRNA CRISPR Lentivector (Human) (Target 1)

K1626702 1.0 ug DNA
EUR 184.8

Peg12 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3769502 1.0 ug DNA
EUR 184.8

Peg10 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4676402 1.0 ug DNA
EUR 184.8

Biotin PEG2 amine *CAS 138529-46-1*

3014-5mg 5 mg
EUR 109
Description: This carbonyl-reactive biotin derivative contains a long arm (~20 angstrom) increase its avidin-binding affinity.

PEG10 (untagged)-Human paternally expressed 10 (PEG10), transcript variant 1

SC318188 10 µg Ask for price

PEG10 (untagged)-Human paternally expressed 10 (PEG10), transcript variant 1

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PEG10 (untagged)-Human paternally expressed 10 (PEG10), transcript variant 1

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Lenti ORF clone of Peg10 (Myc-DDK-tagged) - Mouse paternally expressed 10 (Peg10), transcript variant 1, encoding isoform 1

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PEG10 (GFP-tagged) - Human paternally expressed 10 (PEG10), transcript variant 1

RG231501 10 µg Ask for price

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PEG10 (GFP-tagged) - Human paternally expressed 10 (PEG10), transcript variant 1

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PEG10 (GFP-tagged) - Human paternally expressed 10 (PEG10), transcript variant 1

RG208683 10 µg Ask for price

JBScreen PEG/Salt 1

CS-141 24solutions
EUR 229.9

JBScreen PEG/Salt 1

M-CS-141 24 solutions
EUR 263
Description: JBScreen PEG/Salt 1

Lenti ORF particles, Peg10 (GFP-tagged) - Mouse paternally expressed 10 (Peg10), transcript variant 1, encoding isoform 1, 200ul, >10^7 TU/mL

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Peg10 (Myc-DDK-tagged) - Mouse paternally expressed 10 (Peg10), transcript variant 1

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Peg10 (Myc-DDK-tagged) - Mouse paternally expressed 10 (Peg10), transcript variant 1

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Peg10 (GFP-tagged) - Mouse paternally expressed 10 (Peg10) transcript variant 1, (10ug)

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Peg10 (GFP-tagged) - Mouse paternally expressed 10 (Peg10) transcript variant 1, (10ug)

MG225144 10 µg Ask for price

PEG10 (Myc-DDK-tagged)-Human paternally expressed 10 (PEG10), transcript variant 1

RC208683 10 µg Ask for price

PEG10 (Myc-DDK-tagged)-Human paternally expressed 10 (PEG10), transcript variant 1

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PEG10 (Myc-DDK-tagged)-Human paternally expressed 10 (PEG10), transcript variant 1

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PEG10 (Myc-DDK-tagged)-Human paternally expressed 10 (PEG10), transcript variant 1

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Lenti ORF particles, Peg10 (Myc-DDK-tagged) - Mouse paternally expressed 10 (Peg10), transcript variant 1, encoding isoform 1, 200ul, >10^7 TU/mL

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PEG3 (untagged)-Human paternally expressed 3 (PEG3), transcript variant 1

SC128281 10 µg Ask for price

PEG3 sgRNA CRISPR Lentivector (Human) (Target 1)

K1626502 1.0 ug DNA
EUR 184.8

Peg3 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4341802 1.0 ug DNA
EUR 184.8

PEG3AS sgRNA CRISPR Lentivector (Human) (Target 1)

K1626602 1.0 ug DNA
EUR 184.8

iFluor®488-PEG12-dUTP *1 mM in Tris Buffer (pH 7.5)*

17041 25 nmoles
EUR 101
Description: The dye-modified deoxyuridine 5'-triphosphates are one of the most common methods to produce dye-labelled DNA via the conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

iFluor®488-PEG12-dUTP *1 mM in Tris Buffer (pH 7.5)*

17041-25nmoles 25 nmoles
EUR 99
Description: The dye-modified deoxyuridine 5'-triphosphates are one of the most common methods to produce dye-labelled DNA via the conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

iFluor®555-PEG12-dUTP *1 mM in Tris Buffer (pH 7.5)*

17042 25 nmoles
EUR 101
Description: The dye-modified deoxyuridine 5'-triphosphates are one of the most common methods to produce dye-labelled DNA via the conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

iFluor®555-PEG12-dUTP *1 mM in Tris Buffer (pH 7.5)*

17042-25nmoles 25 nmoles
EUR 99
Description: The dye-modified deoxyuridine 5'-triphosphates are one of the most common methods to produce dye-labelled DNA via the conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

iFluor®647-PEG12-dUTP *1 mM in Tris Buffer (pH 7.5)*

17043 25 nmoles
EUR 101
Description: The dye-modified deoxyuridine 5'-triphosphates are one of the most common methods to produce dye-labeled DNA via conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

iFluor®647-PEG12-dUTP *1 mM in Tris Buffer (pH 7.5)*

17043-25nmoles 25 nmoles
EUR 99
Description: The dye-modified deoxyuridine 5'-triphosphates are one of the most common methods to produce dye-labelled DNA via the conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

JBScreen PEG/Salt 1 - 4

CS-145 4Kits
EUR 689.8

JBScreen PEG/Salt 1 - 4

M-CS-145 4 Kits
EUR 858
Description: JBScreen PEG/Salt 1 - 4

PEG3 (GFP-tagged) - Human paternally expressed 3 (PEG3), transcript variant 1

RG215328 10 µg Ask for price

PEG3 (Myc-DDK-tagged)-Human paternally expressed 3 (PEG3), transcript variant 1

RC215328 10 µg Ask for price

Peg12 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K6370806 1.0 ug DNA
EUR 200.4

Lenti-ORF clone of PEG10 (mGFP-tagged)-Human paternally expressed 10 (PEG10), transcript variant 1

RC223371L2 10 µg Ask for price

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PEG10 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K1626706 1.0 ug DNA
EUR 200.4

Peg12 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3769506 1.0 ug DNA
EUR 200.4

Peg10 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4676406 1.0 ug DNA
EUR 200.4

pEGFP-C3-Bif-1 Plasmid

PVTB00333-2a 2 ug
EUR 427.2

Lenti-ORF clone of PEG10 (Myc-DDK-tagged)-Human paternally expressed 10 (PEG10), transcript variant 1

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pEGFP-PABPN1(1-165aa) Plasmid

PVT14747 2 ug
EUR 390

Lenti ORF clone of Peg10 (mGFP-tagged) - Mouse paternally expressed 10 (Peg10), transcript variant 1, encoding isoform 2

MR225144L4 10 µg Ask for price

Lenti ORF particles, PEG10 (mGFP-tagged) - Human paternally expressed 10 (PEG10), transcript variant 1, 200ul, >10^7 TU/mL

RC208683L4V 200 µl Ask for price

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Lenti ORF particles, PEG10 (mGFP-tagged)-Human paternally expressed 10 (PEG10), transcript variant 1, 200ul, >10^7 TU/mL

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Lenti ORF particles, PEG10 (mGFP-tagged)-Human paternally expressed 10 (PEG10), transcript variant 1, 200ul, >10^7 TU/mL

RC231501L4V 200 µl Ask for price

Lenti ORF particles, PEG10 (mGFP-tagged) - Human paternally expressed 10 (PEG10), transcript variant 1, 200ul, >10^7 TU/mL

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Lenti ORF particles, PEG10 (mGFP-tagged) - Human paternally expressed 10 (PEG10), transcript variant 1, 200ul, >10^7 TU/mL

RC229935L4V 200 µl Ask for price

Lenti ORF particles, PEG10 (Myc-DDK tagged) - Human paternally expressed 10 (PEG10), transcript variant 1, 200ul, >10^7 TU/mL

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Lenti ORF particles, PEG10 (Myc-DDK tagged) - Human paternally expressed 10 (PEG10), transcript variant 1, 200ul, >10^7 TU/mL

RC229935L1V 200 µl Ask for price

Via the AhR-dependent mechanism, Trp metabolites connect bidirectional signaling between the gut microbiome and the brain, mediated via immune, metabolic, and neural (vagal) signaling mechanisms, with downstream effects on behavior and CNS function. These findings shed light on the complex Trp regulation of microbiome-gut-brain axis and add another facet to our understanding that dietary Trp is expected to be a promising noninvasive approach for alleviating systemic diseases.