Retinal pressure autoregulation is an important mechanism that protects the retina by stabilizing retinal blood flow during changes in arterial or intraocular pressure. Similar to other vascular beds, retinal pressure autoregulation is thought to be mediated largely through the myogenic response of small arteries and arterioles which constrict when transmural pressure increases or dilate when it decreases.
Over recent years, we and others have investigated the signaling pathways underlying the myogenic response in retinal arterioles, with particular emphasis on the involvement of different ion channels expressed in the smooth muscle layer of these vessels.
Here, we review and extend previous work on the expression and spatial distribution of the plasma membrane and sarcoplasmic reticulum ion channels present in retinal vascular smooth muscle cells (VSMCs) and discuss their contribution to pressure-induced myogenic tone in retinal arterioles.
This includes new data demonstrating that several key players and modulators of the myogenic response show distinctively heterogeneous expression along the length of the retinal arteriolar network, suggesting differences in myogenic signaling between larger and smaller pre-capillary arterioles.
Neuregulin/Heregulin-1? (NRG-1?/HRG-1?), human recombinant protein |
P1054-1 |
ApexBio |
1 mg |
EUR 3947.00 |
Description: Neuregulin (NRG) is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells and plays an important role in heart structure and function through inducing cardiomyocyte differentiation |
Angiotensin 1/2 (1-7) amide |
A1054-1 |
ApexBio |
1 mg |
EUR 96.00 |
Description: Angiotensin I/II (1-7) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide) is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse. |
Angiotensin 1/2 (1-8) amide |
A1055-1 |
ApexBio |
1 mg |
EUR 96.00 |
Description: The physiologically active peptide angiotensin-2 (angiotensin 1- 8) is yielded from angiotensin-1, a substrate of ACE (angiotensin converting enzyme), by removing a dipeptide. |
Endothelin-1 (1-15), amide, human |
A1111-1 |
ApexBio |
1 mg |
EUR 722.00 |
Description: Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium and have a key role in vascular homeostasis. |
Haptoglobin, (Phenotype 1-1) Human Plasma |
7536-1 |
Biovision |
|
EUR 321.00 |
UK 1 |
C5006-1 |
ApexBio |
1 mg |
EUR 363.00 |
Description: UK 1, an unusual bis-benzoxazole metabolite isolated from Streptomyces sp. 517-02, is an inhibitor of topoisomerase II (Topo II) and hepatitis C viral replication. |
KP372-1 |
C5053-1 |
ApexBio |
1 mg |
EUR 132.00 |
Description: IC50: 30-60 nM for thyroid cancer cells KP372-1 is a specific Akt inhibitor. The phosphatidylinositol 3' kinase (PI3K)/phosphatase, which is a key regulator of cell proliferation and survival, is mutated or activated in various cancers. |
ADWX 1 |
B5722-.1 |
ApexBio |
100 ug |
EUR 583.00 |
Description: ADWX 1 is a potent and selective inhibitor of KV1.3 channel with IC50 values of 1.89 pM and 0.65 nM for Kv1.3 and Kv1.1, respectively [1]. |
Purotoxin 1 |
B5771-.1 |
ApexBio |
100 µg |
EUR 380.00 |
Shz 1 |
B5772-1 |
ApexBio |
1 mg |
EUR 118.00 |
Psalmotoxin 1 |
B5796-.1 |
ApexBio |
100 ug |
EUR 447.00 |
Description: IC50: 0.9 nMPsalmotoxin 1 is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker.Several ASIC subunits described: ASIC1a, ASIC1b, ASIC2a, ASIC2b, and ASIC3 with different kinetics, tissue distribution, and external pH sensitivities. |
TAPI-1 |
B4686-1 |
ApexBio |
1 mg |
EUR 268.00 |
Description: TAPI-1 is an inhibitor of tumour necrosis factor with IC50 value of 8.09 ?M [1].TAPI-1 is an inhibitor of TACE/ADAM17 which catalyzes the cleavage of full-length APP to the soluble N-terminal fragment (sAPP?). |
C14TKL-1 |
B5240-1 |
ApexBio |
1 mg |
EUR 399.00 |
?1-MSH |
B5427-1 |
ApexBio |
1 mg |
EUR 268.00 |
MMK 1 |
B5446-1 |
ApexBio |
1 mg |
EUR 268.00 |
CRSP-1 |
B5452-.1 |
ApexBio |
100 ug |
EUR 415.00 |
Flutax 1 |
B6986-1 |
ApexBio |
1 mg |
EUR 399.00 |
IDE 1 |
B7566-1 |
ApexBio |
1 mg |
EUR 118.00 |
Rbin-1 |
B7823-1 |
ApexBio |
1 mg |
EUR 154.00 |
Description: Rbin-1 is an eukaryotic ribosome assembly inhibitor.All cellular proteins are synthesized by ribosomes, whose biogenesis is a complex multi-step process quickly completed in eukaryotes. |
IL-1-beta Interleukin-1 betaHuman Recombinant Protein |
PROTP01584-1 |
BosterBio |
Regular: 10ug |
EUR 317.00 |
Description: Interleukin-1 beta Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.;The IL-1b is purified by proprietary chromatographic techniques. |
MMP-1 Matrix Metalloproteinase-1 Human Recombinant Protein |
PROTP03956-1 |
BosterBio |
Regular: 20ug |
EUR 317.00 |
Description: MMP 1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 393 amino acids (100-469a.a) and having a molecular mass of 45kDa. MMP 1 is fused to a 23 amino acid His-tag at N-terminus. |
Anti-HO-1 Monoclonal Antibody (HO-1-2) |
M00253-1 |
BosterBio |
1mg |
EUR 397.00 |
Description: Mouse Monoclonal HO-1 Antibody (HO-1-2). Validated in Flow Cytometry, IHC, WB and tested in Human, Mouse, Rat. |
RN-1 (hydrochloride) |
C4247-1 |
ApexBio |
1 mg |
EUR 112.00 |
Description: RN-1 (hydrochloride) is a brain-penetrant, potent and irreversible LSD1 inhibitor with IC50 values of 10-70 nM [1]. Lysine-specific demethylase 1 (LSD1) is a flavin-dependent monoamine oxidase that demethylate mono- and di-methylated lysines, specifically histone 3, lysines 4 and 9. |
Teicoplanin A3-1 |
C4943-1 |
ApexBio |
1 mg |
EUR 326.00 |
Description: Teicoplanin A3-1, also known as Antibiotic L 17054, is a glycopeptide antibiotic derived from Actinoplanes teichomyceticus and produces a potent broad spectrum antibiotic activity against gram-positive bacteria. |
TASIN-1 hydrochloride |
B2088-1 |
Biovision |
|
EUR 142.00 |
PACAP 1-38 |
B6625-1 |
ApexBio |
1 mg |
EUR 347.00 |
Sphingosine-1-phosphate |
B6707-1 |
ApexBio |
1 mg |
EUR 181.00 |
Description: Sphingosine-1-phosphate is an endogenous second messenger that involved in cell proliferation and survival and is a ligand for S1PR1 [1] [2]. |
HPGDS inhibitor 1 |
B1046-1 |
ApexBio |
1 mg |
EUR 181.00 |
Description: HPGDS inhibitor 1 is an oral potent and selective inhibitor of hematopoietic prostaglandin D synthase (HPGDS) with IC50 value of 0.7nM [1].Prostaglandin D2 (PGD2) is a mediator of allergy and inflammation. |
CDK7-IN-1 |
B4665-1 |
ApexBio |
1 mg |
EUR 358.00 |
LPA2 antagonist 1 |
B4726-1 |
ApexBio |
1 mg |
EUR 319.00 |
PACAP 1-27 |
B5075-1 |
ApexBio |
1 mg |
EUR 290.00 |
Nociceptin (1-7) |
B5087-1 |
ApexBio |
1 mg |
EUR 399.00 |
Hemokinin 1 (mouse) |
B5127-1 |
ApexBio |
1 mg |
EUR 321.00 |
GIP (1-39) |
B5280-1 |
ApexBio |
1 mg |
EUR 609.00 |
JMV 390-1 |
B5317-1 |
ApexBio |
1 mg |
EUR 242.00 |
Hemokinin 1 (human) |
B5318-1 |
ApexBio |
1 mg |
EUR 340.00 |
Echistatin, ?1 isoform |
B5391-.1 |
ApexBio |
100 ug |
EUR 583.00 |
SL 0101-1 |
B9008-1 |
ApexBio |
1 mg |
EUR 163.00 |
StemRegenin 1 (hydrochloride) |
C3551-1 |
ApexBio |
1 mg |
EUR 118.00 |
Description: IC50: 127 nM in CD34+ cellsStemRegenin 1 is an aryl hydrocarbon receptor signaling antagonist.The aryl hydrocarbon receptor (AhR ) is a protein that is encoded by the AHR gene. |
IDO-IN-1 |
C3211-1 |
ApexBio |
1 mg |
EUR 139.00 |
Description: IC50: 59 nMIDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor. |
EZSolution? TAPI-1 |
2537-1 |
Biovision |
|
EUR 381.00 |
(R)-Perharidine-1 |
2615-1 |
Biovision |
|
EUR 164.00 |
(1-328) RAD51D (1-328 a.a.) Human Recombinant Protein |
PROTO75771-1 |
BosterBio |
Regular: 10ug |
EUR 317.00 |
Description: RAD51D (1-328) Human Recombinant produced in E. coli is. a single polypeptide chain containing 351 amino acids and having a molecular mass of 37.4kDa. RAD51D (1-328) is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
XMIR-1 RNA oligo miRNA-1-3p with Xmotif |
XMIR-1 |
SBI |
10 rxn |
EUR 438.00 |
|
AXMIR-1 RNA oligo anti-miRNA-1-3p with Xmotif |
AXMIR-1 |
SBI |
10 reactions |
EUR 438.00 |
|
Human KRAB-associated Protein 1 (KAP-1) AssayMax ELISA Kit |
EK2802-1 |
AssayPro |
96 Well Plate |
EUR 477.00 |
Human Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit |
EI2200-1 |
AssayPro |
96 Well Plate |
EUR 477.00 |
Human Interleukin-1-alpha (IL-1-alpha) AssayMax ELISA Kit |
EI2301-1 |
AssayPro |
96 Well Plate |
EUR 477.00 |
Human Plasminogen Activator Inhibitor-1 (PAI-1) AssayMax ELISA Kit |
EP1100-1 |
AssayPro |
96 Well Plate |
EUR 417.00 |
Mouse Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit |
EMI2200-1 |
AssayPro |
96 Well Plate |
EUR 477.00 |
Envelope-1, Dengue Virus Subtype 1 Recombinant Protein, Insect Cells |
PROTB1PNJ5-1 |
BosterBio |
Regular: 10ug |
EUR 317.00 |
Description: Recombinant Dengue Virus Subtype 1 produced in Insect Cells is a polypeptide chain containing amino acids 281-675 and having a molecular weight of approximately 50kDa. ;Dengue Envelope-1 is purified by proprietary chromatographic technique. |
TGF-b-1 Transforming Growth Factor-beta 1 Human protein |
PROTP01137-1 |
BosterBio |
Regular: 2.5ug |
EUR 1157.00 |
Description: Human Transforming Growth Factor-beta 1 purified from Human Platelets having a molecular mass of 25kDa.;The TGF-b 1 is purified by proprietary chromatographic techniques. |
MCP-1 Monocyte Chemotactic Protein-1 Mouse Recombinant Protein (CCL2) |
PROTP10148-1 |
BosterBio |
Regular: 10ug |
EUR 317.00 |
Description: Monocyte Chemotactic Protein-1 Mouse Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 125 amino acids and having a molecular mass of 14 kDa. ;The MCP-1 is purified by proprietary chromatographic techniques. |
MCP-1 Monocyte Chemotactic Protein-1 Human Recombinant Protein (CCL2) |
PROTP13500-1 |
BosterBio |
Regular: 20ug |
EUR 317.00 |
Description: Monocyte Chemotactic Protein-1 Human Recombinant also known as Monocyte Chemotactic and Activating Factor (MCAF) produced in E.Coli is a non-glycosylated, Polypeptide chain containing 76 amino acids and having a molecular mass of 8.6kDa. ;The MCP-1 is purified by proprietary chromatographic techniques. |
Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 |
M04431-1 |
BosterBio |
100uL |
EUR 385.00 |
Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human |
GAD1 iso1 Glutamate Decarboxylase 1 Isoform-1 Human Recombinant Protein |
PROTQ99259-1 |
BosterBio |
Regular: 20ug |
EUR 317.00 |
Description: GAD1 iso1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 617 amino acids (1-594 a.a) and having a molecular mass of 69.3kDa. GAD1 iso1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
B-Raf IN 1 |
B4727-1 |
ApexBio |
1 mg |
EUR 118.00 |
Nociceptin (1-13)NH2 |
B5102-1 |
ApexBio |
1 mg |
EUR 184.00 |
JIP-1 (153-163) |
B5130-1 |
ApexBio |
1 mg |
EUR 399.00 |
Nogo-66 (1-40) |
B5247-1 |
ApexBio |
1 mg |
EUR 609.00 |
Orphanin FQ (1-11) |
B5497-1 |
ApexBio |
1 mg |
EUR 226.00 |
R-1 Methanandamide Phosphate |
C3352-1 |
ApexBio |
1 mg |
EUR 126.00 |
Description: R-1 Methanandamide Phosphate,a water soluble prodrug analog of AEA, exhibited similar activity to that of AEA in the growth inhibition of C6 glioma cells[1]. Arachidonoyl ethanolamide (AEA) was the first endogenous cannabinoid (CB). |
Ginkgolic Acid C15:1 |
C3421-1 |
ApexBio |
1 mg |
EUR 118.00 |
Description: Ginkgolic acid is an alkylphenol derivative that causes allergic skin inflammation. IC50 values of ginkgolic acid against the SUMOylation of RanGAP1-C2 are 3.0 ?M. Ginkgolic Acid, a Major Component of Ginkgo biloba Extract, inhibited SUMOylation in vitro and in vivo [1]. |
Individual Reaction Mix 1 |
G065-1 |
ABM |
200 reactions |
EUR 167.00 |
Anti-PARP-1 Antibody |
A00122-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse. |
Anti-Presenilin 1 Antibody |
A00138-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat. |
Anti-PAI-1 Antibody |
A00637-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat. |
Anti-Flk-1 Antibody |
A00901-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse. |
Anti-EDG-1 Antibody |
A01502-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat. |
Anti-ROBO-1 Antibody |
A01530-1 |
BosterBio |
100ug |
EUR 455.00 |
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
Anti-Bag-1 Antibody |
A02423-1 |
BosterBio |
50 ul |
EUR 397.00 |
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat. |
Anti-TUB 1 Antibody |
A02917-1 |
BosterBio |
100ug/vial |
EUR 294.00 |
Anti-Dok-1 Antibody |
A03039-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat. |
Anti-TFIIIB90-1 Antibody |
A03761-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse. |
Anti-Atrophin-1 Antibody |
A03828-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-CNG-1 Antibody |
A05494-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat. |
ANP (1-11), rat |
A1009-1 |
ApexBio |
1 mg |
EUR 84.00 |
Description: Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, endothelin, and sympathetic stimulation. |
alpha-1 antitrypsin fragment |
A1051-1 |
ApexBio |
1 mg |
EUR 108.00 |
Description: Alpha-1 antitrypsin (A1AT) (H2N-Leu-Gln-His-Leu-Glu-Asn-Glu-Leu-Thr-His-Asp-Ile-Ile-Thr-Lys-OH), which is known as serum trypsin inhibitor, is a protease inhibitor belonging to the serpin superfamily. |
BNP (1-32), human |
A1105-1 |
ApexBio |
1 mg |
EUR 177.00 |
Description: Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). |
Anti-Periphilin 1 Antibody |
A06996-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse. |
Anti-Lyl-1 Antibody |
A07491-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat. |
Anti-GLI-1 Antibody |
A07972-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-Cerebellin 1 Antibody |
A09176-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-DOC-1 Antibody |
A09467-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse. |
Beta-Amyloid (1-11) |
A1002-1 |
ApexBio |
1 mg |
EUR 102.00 |
Description: Beta-amyloid (1-11) (Abeta or A?) (C56H76N16O22) is a peptide with the sequence H-{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}-OH,which is processed from the Amyloid precursor protein. |
Amyloid ?-Protein (1-15) |
A1003-1 |
ApexBio |
1 mg |
EUR 113.00 |
Description: Beta-amyloid protein (A beta), a 39-43 amino acid peptide composed of a portion of the transmembrane domain and the extracellular domain of the amyloid precursor protein (APP), is also the principal component of amyloid. |
Anti-NPDC-1 Antibody |
A12846-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat. |
StemRegenin 1, Free base |
2642-1 |
Biovision |
|
EUR 131.00 |
IGF-1, human recombinant |
P1016-.1 |
ApexBio |
100 µg |
EUR 763.00 |
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue |
Supercoiled pHOT-1 DNA |
TG2030-1 |
TopoGen |
25 ug |
EUR 246.00 |
Relaxed pHOT-1 DNA |
TG2035-1 |
TopoGen |
25 ug |
EUR 246.00 |
Human Insulin-like Growth Factor 1 (IGF-1) AssayMax ELISA Kit |
EI1001-1 |
AssayPro |
96 Well Plate |
EUR 477.00 |
Human Heat Shock Factor Protein 1 (HSF 1) AssayMax ELISA kit |
EH5215-1 |
AssayPro |
96 Well Plate |
EUR 417.00 |
Mouse Insulin-like Growth Factor 1 (IGF-1) AssayMax ELISA Kit |
EMI1001-1 |
AssayPro |
96 Well Plate |
EUR 477.00 |
GLP-1 Glucagon Like Peptide-1 (31 a.a.) Human Recombinant Protein |
PROTP01275-1 |
BosterBio |
Regular: 50ug |
EUR 317.00 |
Description: Glucagon Like Peptide-1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 31 amino acids and having a molecular mass of 3298.7 Dalton. The GLP-1 is purified by proprietary chromatographic techniques. |
IL-1-alpha Interleukin-1 alpha Mouse Recombinant Protein, His Tag |
PROTP01582-1 |
BosterBio |
Regular: 20ug |
EUR 317.00 |
Description: IL 1 alpha Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.4kDa.;IL 1 alpha is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
IL-1-alpha Interleukin-1 alpha Human Recombinant Protein, His Tag |
PROTP01583-1 |
BosterBio |
Regular: 20ug |
EUR 317.00 |
Description: IL-1A Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 159 amino acids fragment (113-271) with an amino-terminal hexahistidine tag and having a total molecular mass of 22.5kDa. ;The Interleukin-1 alpha His-tag is purified by proprietary chromatographic techniques. |
IL-1-beta Interleukin-1 beta Mouse Recombinant Protein, His Tag |
PROTP10749-1 |
BosterBio |
Regular: 25ug |
EUR 317.00 |
Description: Interleukin-1 beta Mouse Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 189 amino acids and having a molecular mass of 21 kDa. ;The IL-1b is fused to His-Tag and purified by proprietary chromatographic techniques. |
IL-1-alpha Interleukin-1 alpha Rat Recombinant Protein, His Tag |
PROTP16598-1 |
BosterBio |
Regular: 20ug |
EUR 317.00 |
Description: IL 1 alpha Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.2kDa. |
VAMP2 (1-94) Synaptobrevin-2 (1-94 a.a) Human Recombinant Protein |
PROTP63027-1 |
BosterBio |
Regular: 5ug |
EUR 317.00 |
Description: VAMP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 118 amino acids (1-94 a.a) and having a molecular mass of 12.8kDa.;VAMP2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
IL1RL1 Human, Interleukin-1 Receptor Like-1 Human Recombinant Protein, Sf9 |
PROTQ01638-1 |
BosterBio |
Regular: 10ug |
EUR 317.00 |
Description: IL 1RL1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (19-328 a.a.) and fused to an 8 aa His Tag at C-terminus containing a total of 318 amino acids and having a molecular mass of 36.0kDa.;IL 1RL1 shows multiple bands between 40-57kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques. |
DCTN2 (1-406) Dynactin 2 (1-406 a.a.) Human Recombinant Protein |
PROTQ13561-1 |
BosterBio |
Regular: 20ug |
EUR 317.00 |
Description: Dynactin 2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 429 amino acids (1-406 a.a) and having a molecular mass of 47.2kDa.;DCTN2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
STX1A (1-265) Syntaxin-1A (1-265 a.a) Human Recombinant Protein |
PROTQ16623-1 |
BosterBio |
Regular: 10ug |
EUR 317.00 |
Description: STX1A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 265 amino acids (1-265 a.a) and having a molecular mass of 30.7kDa.  |
Human Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA810A-1 components) |
RA820A-1 |
SBI |
20 profiles |
EUR 1297.00 |
|
Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA812A-1 components) |
RA822A-1 |
SBI |
20 profiles |
EUR 1297.00 |
|
Human Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800A-1, RA805A-1, RA810A-1 and EXOTC50A-1 components) |
RA820TC-1 |
SBI |
20 profiles |
EUR 1618.00 |
|
Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800A-1, RA805A-1, RA810A-1 and EXOTC50A-1 components) |
RA821TC-1 |
SBI |
20 profiles |
EUR 1618.00 |
|
(1R,1'S,3'R/1R,1'R,3'S)-L-054,264 |
B7057-1 |
ApexBio |
1 mg |
EUR 242.00 |
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species] |
A1067-1 |
ApexBio |
1 mg |
EUR 108.00 |
Description: Sequence: LEU-GLU-ASP-GLY-PRO-LYS-PHE-LEUeukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. |
Human pre-microRNA Expression Construct Lenti-miR-181a-1 + 181b-1 MI0000270 |
PMIRH181a1PA-1 |
SBI |
Bacterial Streak |
EUR 684.00 |
|
PSG1 Human, Pregnancy Specific Beta-1-Glycoprotein 1 Human Recombinant Protein, Sf9 |
PROTP11464-1 |
BosterBio |
Regular: 10ug |
EUR 317.00 |
Description: PSG1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 394 amino acids (35-419a.a.) and having a molecular mass of 44.6kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). PSG1 is expressed with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques. |
1H-1-ethyl Candesartan Cilexetil |
C5023-1 |
ApexBio |
1 mg |
EUR 112.00 |
Description: 1H-1-ethyl Candesartan Cilexetil, which is a process-related impurity commonly found in the bulk synthesis of candesartan cilexetil, is a potent, long-acting, and selective angiotensin II type 1 receptor (AT1) antagonist. |
Amyloid ?-Peptide (1-42) (human) |
B6057-.1 |
ApexBio |
100 ug |
EUR 276.00 |
HIV-1 Tat Protein Peptide |
B1433-1 |
ApexBio |
1 mg |
EUR 128.00 |
Description: HIV-1 Tat Protein Peptide |
[Nphe1]Nociceptin(1-13)NH2 |
B5089-1 |
ApexBio |
1 mg |
EUR 583.00 |
Galanin (1-15) (porcine, rat) |
B5115-1 |
ApexBio |
1 mg |
EUR 519.00 |
187-1, N-WASP inhibitor |
B5251-1 |
ApexBio |
1 mg |
EUR 399.00 |
Galanin (1-29) (rat, mouse) |
B5325-1 |
ApexBio |
1 mg |
EUR 399.00 |
GLP-1 (9-36) amide |
B5404-1 |
ApexBio |
1 mg |
EUR 561.00 |
Anti-TNF Receptor 1 Antibody |
A00294-1 |
BosterBio |
200ug |
EUR 522.00 |
Description: Rabbit Polyclonal TNF Receptor 1 Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat. |
Anti-Galectin 1/Lgals1 Antibody |
A00470-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Anti-LOX-1/OLR1 Antibody |
A00760-1 |
BosterBio |
100ug/vial |
EUR 294.00 |
Anti-Syndecan-1/SDC1 Antibody |
A00991-1 |
BosterBio |
100ug/vial |
EUR 294.00 |
Anti-IRAK-1/IRAK1 Antibody |
A01021-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Anti-Neurexin 1/NRXN1 Antibody |
A01490-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Anti-Hexokinase 1/HK1 Antibody |
A01504-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Anti-Synaptotagmin 1/SYT1 Antibody |
A02314-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Anti-Syntenin-1 Monoclonal Antibody |
A02475-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Mouse Monoclonal Antibody for Syntenin-1 Antibody (SDCBP) detection. Tested with WB in Human, Rat, Dog, Pig. |
Anti-Dsg1/Desmoglein 1 Antibody |
A02655-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for Dsg1 Antibody (DSG1) detection.tested for IHC, WB in Human, Mouse, Rat. |
Anti-CAF-1 p150 Antibody |
A02732-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for CAF-1 p150 Antibody (CHAF1A) detection. Tested with WB in Human, Mouse. |
Anti-Talin 1/TLN1 Antibody |
A02859-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Anti-Islet 1/ISL1 Antibody |
A02969-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Anti-Musashi 1/Msi1 Antibody |
A05052-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Anti-CHST8/Galnac4St 1 Antibody |
A10989-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal CHST8/Galnac4St 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
Parathyroid Hormone (1-34), bovine |
A1114-1 |
ApexBio |
1 mg |
EUR 166.00 |
Description: Parathyroid hormone (PTH) is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid, which is secreted by the chief cell of the parathyroid glands as a polypeptide containing 84 amino acids. |
Parathyroid hormone (1-34) (human) |
A1129-1 |
ApexBio |
1 mg |
EUR 166.00 |
Description: Parathyroid hormone (1-34) (human), (C181H291N55O51S2), a peptide with the sequence H2N-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 4117.72. |
Anti-Pyrophosphatase 1/PPA1 Antibody |
A07485-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Anti-TCP-1 eta Antibody |
A08169-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for TCP-1 eta Antibody (CCT7) detection. Tested with WB in Human, Mouse, Rat. |
Anti-Relaxin 1/RLN1 Antibody |
A08367-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Anti-TCP-1 zeta Antibody |
A09373-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Rabbit Polyclonal Antibody for TCP-1 zeta Antibody (CCT6A) detection.tested for WB in Human, Mouse, Rat. |
Indo-1, AM ester: (20x50ug) |
50043-1 |
Biotium |
20ST |
EUR 237.00 |
Description: Minimum order quantity: 1 unit of 20ST |
RedDot 1, 200X in water |
40060-1 |
Biotium |
1mL |
EUR 467.00 |
Description: Minimum order quantity: 1 unit of 1mL |
EZSolution? StemRegenin 1, Free base |
2643-1 |
Biovision |
|
EUR 142.00 |
Dr. P Kit-Solution 1 |
K2021010-1 |
Biochain |
50 ml |
EUR 204.00 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
IL-1 beta, rat recombinant |
P1019-1 |
ApexBio |
1 mg |
EUR 7288.00 |
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells. Both IL-1? and IL-1? bind to the same receptor and have similar biological properties. |
ApoA-1, human recombinant protein |
P1052-.1 |
ApexBio |
100 µg |
EUR 313.00 |
Description: Apolipoprotein A-1 (ApoA-1) is a glycoprotein produced in the liver and intestine that is the major protein component of high density lipoprotein (HDL) particles. ApoA-1 is involved in the reverse transport of cholesterol from peripheral tissues to the liver for recycling and excretion. |
ApoA-1, human recombinant protein |
P1052-1 |
ApexBio |
1 mg |
EUR 1553.00 |
Description: Apolipoprotein A-1 (ApoA-1) is a glycoprotein produced in the liver and intestine that is the major protein component of high density lipoprotein (HDL) particles. ApoA-1 is involved in the reverse transport of cholesterol from peripheral tissues to the liver for recycling and excretion. |
WNT-1, human recombinant protein |
P1068-1 |
ApexBio |
1 mg |
EUR 6940.00 |
Description: The WNT gene family compose of structurally related genes that encode secreted signaling proteins. These proteins have been involved in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. |
Anti-Galectin 1/LGALS1 Antibody |
PB9240-1 |
BosterBio |
100ug/vial |
EUR 334.00 |
Recombinant Human Gremlin-1 Protein |
PROTO60565-1 |
BosterBio |
50ug |
EUR 317.00 |
Description: Gremlin-1 (isoform-1) belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Gremlin is highly expressed in the small intestine, fetal brain, and colon and lower expression in brain, prostate, pancreas and skeletal muscle. Gremlin-1 regulates multiple functions in early development by specifically binding to and inhibiting the function of BMP-2, -4, and -7. It also plays a role in carcinogenesis and kidney branching morphogenesis. Recombinant Gremlin-1 is a 18.3 kDa protein containing 160 amino acid residues. |
ORM1 Orosomucoid 1 Human protein |
PROTP02763-1 |
BosterBio |
Regular: 10ug |
EUR 317.00 |
Description: The Human Orosomucoid 1 produced from Human pooled serum has a molecular mass of 21.56kDa (calculated without glycosylation) containing 183 amino acid residues. |
Recombinant Human Galectin-1 Protein |
PROTP09382-1 |
BosterBio |
50ug |
EUR 317.00 |
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues. |
Recombinant Human PECAM-1 Protein |
PROTP16284-1 |
BosterBio |
50ug |
EUR 317.00 |
Description: PECAM is transmembrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. It is highly expressed at endothelial cell junctions, and also expressed in platelets and in most leukocyte sub-types. The primary function of PECAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. PECAM-1 has been implicated in the pathogenesis of various inflammation related disorders, including thrombosis, multiple sclerosis (MS), and rheumatoid arthritis. The human PECAM-1 gene codes for a 738 amino acid transmembrane glycoprotein containing a 118 amino acid cytoplasmic domain, a 19 amino acid transmembrane domain, and a 574 amino acid extracellular domain. Recombinant human PECAM-1 is a 572 amino acid glycoprotein comprising the extracellular domain of PECAM-1. Monomeric glycosylated PECAM-1 migrates at an apparent molecular weight of approximately 80.0-95.0 kDa by SDS-PAGE analysis under reducing conditions |
Anti-Presenilin 1 Monoclonal Antibody |
M00138-1 |
BosterBio |
100ug |
EUR 397.00 |
Description: Rabbit Monoclonal Presenilin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
Anti-Galectin 1 Monoclonal Antibody |
M00470-1 |
BosterBio |
100ug |
EUR 397.00 |
Description: Rabbit Monoclonal Galectin 1 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat. |
Anti-DJ-1 Monoclonal Antibody |
M00757-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Mouse Monoclonal DJ-1 Antibody. Validated in IHC, WB and tested in Bovine, Human. |
Anti-Enolase 1 Monoclonal Antibody |
M01250-1 |
BosterBio |
100ul |
EUR 397.00 |
Description: Anti-Enolase 1 Monoclonal Antibody tested in WB, IF, ICC, IHC, reactive to Human, rat, mouse, cow, pig, horse |
Our immunohistochemical investigations have also highlighted the presence of actin-containing microstructures called myobridges that connect the retinal VSMCs to one another. Although further work is still needed, studies to date investigating myogenic mechanisms in the retina have contributed to a better understanding of how blood flow is regulated in this tissue. They also provide a basis to direct future research into retinal diseases where blood flow changes contribute to the pathology.